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Tdark
ARPC5L
Actin-related protein 2/3 complex subunit 5-like protein

Protein Summary
Description
May function as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000259477
  • ENSP00000259477
  • ENSG00000136950
  • ENST00000353214
  • ENSP00000345361

Symbol
  • ARC16-2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.99
transcription factor binding site profile
0.88
transcription factor perturbation
0.88
disease perturbation
0.83
virus perturbation
0.64


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.99   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 53   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.99   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 53   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0