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Tchem
AURKAIP1
Aurora kinase A-interacting protein

Protein Summary
Description
May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000321751
  • ENSP00000319778
  • ENSG00000175756
  • ENST00000338338
  • ENSP00000340656
  • ENST00000338370
  • ENSP00000342676
  • ENST00000378853
  • ENSP00000368130

Symbol
  • AIP
  • AKIP
  • MRPS38
  • AIP
  • AKIP
  • MRP-S38
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.96
kinase perturbation
0.88
transcription factor binding site profile
0.77
histone modification site profile
0.76
transcription factor
0.69


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.23   (req: < 5)
Gene RIFs: 11   (req: <= 3)
Antibodies: 68   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.23   (req: >= 5)
Gene RIFs: 11   (req: > 3)
Antibodies: 68   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0