Protein Summary
Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) nuclear localization.
- ENST00000280780
- ENSP00000280780
- ENSG00000189319
- ENST00000337318
- ENSP00000338532
- ENST00000392754
- ENSP00000376509
- KIAA0140
- SMP
- smp
- KIAA0140
- bA12J10.2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor binding site profile | 0.89 | ||
disease perturbation | 0.83 | ||
transcription factor | 0.74 | ||
tissue sample | 0.69 | ||
PubMedID | 0.68 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 223.07 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 39 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 223.07 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 39 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0