Tbio MICU3 Calcium uptake protein 3, mitochondrial

Protein Summary

Description

May play a role in mitochondrial calcium uptake.

Uniprot Accession IDs

• Q86XE3
• Q8IYZ3

Gene Name

• MICU3

Ensembl ID

• ENST00000318063
• ENSP00000321455
• ENSG00000155970

Symbol

• EFHA2
• EFHA2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.85
microRNA	0.78
trait	0.75
gene perturbation	0.59
tissue sample	0.5

Protein Classes

PANTHER Classes

Protein / Calcium-binding Protein / Intracellular Calcium-sensing Protein / Calmodulin / Calcium Uptake Protein 3, Mitochondrial

DTO Classes

Protein / Calcium-binding Protein / Intracellular Calcium-sensing Protein / Calmodulin / Calcium Uptake Protein 3, Mitochondrial

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.58   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 57   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.58   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 57   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0