BTN2A1
Butyrophilin subfamily 2 member A1
Protein Summary
This gene encodes a member of the immunoglobulin superfamily. The gene is located in a cluster of butyrophilin-like genes in the juxta-telomeric region of the major histocompatibility complex on chromosome 6. A pseudogene of this gene has been identified in this cluster. The encoded protein is an integral plasma membrane protein involved in lipid, fatty-acid, and sterol metabolism. Alterations in this gene may be associated with several disease states including metabolic syndrome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
- ENST00000312541
- ENSP00000312158
- ENSG00000112763
- ENST00000429381
- ENSP00000416945
- ENST00000469185
- ENSP00000419043
- ENST00000541522
- ENSP00000443909
- BT2.1
- BTF1
- BTF1
- BT2.1
- BTN2.1
- DJ3E1.1
- BK14H9.1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
protein domain | 1 | ||
virus perturbation | 0.76 | ||
phenotype | 0.6 | ||
tissue sample | 0.58 | ||
tissue | 0.57 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 59.36 (req: < 5)
Gene RIFs: 16 (req: <= 3)
Antibodies: 220 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 59.36 (req: >= 5)
Gene RIFs: 16 (req: > 3)
Antibodies: 220 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0