Tbio LMAN1L Protein ERGIC-53-like

Protein Summary

Description

This gene encodes a mannose-binding type 1 transmembrane protein that contains an N-terminal lectin-like carbohydrate recognition domain. The encoded protein is similar in structure to lectins found in leguminous plants. This lectin is thought to transport newly synthesized glycoproteins from the endoplasmic reticulum (ER) to the ER-Golgi intermediate compartment. [provided by RefSeq, Jan 2017]

Uniprot Accession IDs

• Q9HAT1
• Q6UWN2

Gene Name

• LMAN1L

Ensembl ID

• ENST00000309664
• ENSP00000310431
• ENSG00000140506
• ENST00000379709
• ENSP00000369031

Symbol

• ERGL
• ERGL
• ERGIC-53L

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.58
PubMedID	0.48
cell line	0.44
tissue	0.4
biological term	0.36

Protein Classes

PANTHER Classes

Protein / Membrane Traffic Protein / Protein Ergic-53-like

DTO Classes

Protein / Transporter / Protein Ergic-53-like

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.35   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 100   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.35   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 100   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0