Tbio ZNF131 Zinc finger protein 131

Protein Summary

Description

Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity). May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling.

Uniprot Accession IDs

• P52739
• B4DRL3
• Q6PIF0

Gene Name

• ZNF131

Ensembl ID

• ENST00000306938
• ENSP00000305804
• ENSG00000172262
• ENST00000505606
• ENSP00000423945
• ENST00000509156
• ENSP00000426504
• ENST00000509634
• ENSP00000421246

Symbol

• ZBTB35
• pHZ-10

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.97
kinase perturbation	0.84
co-expressed gene	0.76
virus perturbation	0.72
cell line	0.7

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.84   (req: < 5)

Gene RIFs: 9   (req: <= 3)

Antibodies: 261   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.84   (req: >= 5)

Gene RIFs: 9   (req: > 3)

Antibodies: 261   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0