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Tbio
SLC43A2
Large neutral amino acids transporter small subunit 4

Protein Summary
Description
Sodium-, chloride-, and pH-independent high affinity transport of large neutral amino acids. This gene encodes a member of the L-amino acid transporter-3 or SLC43 family of transporters. The encoded protein mediates sodium-, chloride-, and pH-independent transport of L-isomers of neutral amino acids, including leucine, phenylalanine, valine and methionine. This protein may contribute to the transfer of amino acids across the placental membrane to the fetus. [provided by RefSeq, Mar 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000301335
  • ENSP00000301335
  • ENSG00000167703
  • ENST00000382147
  • ENSP00000371582
  • ENSG00000278550
  • ENST00000412517
  • ENSP00000408284
  • ENST00000571650
  • ENSP00000461382
  • ENST00000612931
  • ENSP00000483848
  • ENST00000613070
  • ENSP00000484291
  • ENST00000634102
  • ENSP00000488355

Symbol
  • LAT4
  • LAT4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.89
histone modification site profile
0.78
transcription factor
0.77
kinase perturbation
0.71
tissue sample
0.65


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.9   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 107   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.9   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 107   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0