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Tbio
FEZF2
Fez family zinc finger protein 2

Protein Summary
Description
Transcription repressor. Required for the specification of corticospinal motor neurons and other subcerebral projection neurons. May play a role in layer and neuronal subtype-specific patterning of subcortical projections and axonal fasciculation. Controls the development of dendritic arborization and spines of large layer V pyramidal neurons. May be involved in innate immunity (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000283268
  • ENSP00000283268
  • ENSG00000153266
  • ENST00000475839
  • ENSP00000418804
  • ENST00000486811
  • ENSP00000418589

Symbol
  • FEZL
  • ZNF312
  • FEZ
  • TOF
  • FEZL
  • FKSG36
  • ZFP312
  • ZNF312
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0.88
molecular function
0.67
tissue sample
0.65
PubMedID
0.64
virus perturbation
0.64


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 302.3   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 117   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 302.3   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 117   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 22
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0