ABCA12
ATP-binding cassette sub-family A member 12
Protein Summary
Probable transporter involved in lipid homeostasis. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily, which is the only major ABC subfamily found exclusively in multicellular eukaryotes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
- ENST00000272895
- ENSP00000272895
- ENSG00000144452
- ENST00000389661
- ENSP00000374312
- ABC12
- LI2
- ICR2B
- ARCI4A
- ARCI4B
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
molecular function | 1 | ||
cell type or tissue | 0.85 | ||
protein domain | 0.85 | ||
cellular component | 0.71 | ||
biological process | 0.64 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 238.77 (req: < 5)
Gene RIFs: 40 (req: <= 3)
Antibodies: 106 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 238.77 (req: >= 5)
Gene RIFs: 40 (req: > 3)
Antibodies: 106 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 21
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0