Tbio CIB3 Calcium and integrin-binding family member 3

Protein Summary

Description

This gene product shares a high degree of sequence similarity with DNA-dependent protein kinase catalytic subunit-interacting protein 2 in human and mouse, and like them may bind the catalytic subunit of DNA-dependent protein kinases. The exact function of this gene is not known. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Uniprot Accession IDs

• Q96Q77
• E7EUX1
• Q2M1W0
• Q6ISP1

Gene Name

• CIB3

Ensembl ID

• ENST00000269878
• ENSP00000269878
• ENSG00000141977
• ENST00000379859
• ENSP00000369188

Symbol

• KIP3
• KIP3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.59
cell line	0.54
gene perturbation	0.47
tissue	0.44
protein domain	0.41

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.76   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 122   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.76   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 122   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0