Tbio KIAA1109 Transmembrane protein KIAA1109

Protein Summary

Description

This gene is located on the long arm of chromosome 4 in a region that is associated with susceptibility to celiac disease. The encoded protein is similar to a Chinese hamster protein that is associated with spermatocyte and adipocyte differentiation. The C-terminus of the protein is also similar to a Caenorhabditis elegans protein that plays a role in lipid storage. In mammals, this protein is thought to function in the regulation of epithelial growth and differentiation, and in tumor development. [provided by RefSeq, Oct 2009]

Uniprot Accession IDs

• Q2LD37
• Q4W598
• Q5CZA9
• Q6ZS70
• Q6ZV75
• Q86XA5
• Q8WVD8
• Q9H742
• Q9NT48
• Q9NTC3
• Q9NTI4
• Q9P2H6
• Q9UPP3

Gene Name

• KIAA1109

Ensembl ID

• ENST00000264501
• ENSP00000264501
• ENSG00000138688
• ENST00000388738
• ENSP00000373390

Symbol

• FSA
• KIAA1371
• FSA
• Tweek
• ALKKUCS

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.88
transcription factor perturbation	0.8
phenotype	0.78
tissue sample	0.66
cell type or tissue	0.64

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 68.42   (req: < 5)

Gene RIFs: 13   (req: <= 3)

Antibodies: 15   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 68.42   (req: >= 5)

Gene RIFs: 13   (req: > 3)

Antibodies: 15   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0