OCIAD1
OCIA domain-containing protein 1
Protein Summary
Maintains stem cell potency (By similarity). Increases STAT3 phosphorylation and controls ERK phosphorylation (By similarity). May act as a scaffold, increasing STAT3 recruitment onto endosomes (By similarity). Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer (PubMed:20515946).
- ENST00000264312
- ENSP00000264312
- ENSG00000109180
- ENST00000381473
- ENSP00000370882
- ENST00000396448
- ENSP00000379725
- ENST00000425583
- ENSP00000416943
- ENST00000444354
- ENSP00000399656
- ENST00000508293
- ENSP00000423002
- ENST00000513391
- ENSP00000423909
- ASRIJ
- OCIA
- OCIA
- ASRIJ
- TPA018
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
small molecule perturbation | 0.95 | ||
disease perturbation | 0.83 | ||
ligand (protein) perturbation | 0.83 | ||
histone modification site profile | 0.82 | ||
transcription factor binding site profile | 0.8 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 27.32 (req: < 5)
Gene RIFs: 11 (req: <= 3)
Antibodies: 203 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 27.32 (req: >= 5)
Gene RIFs: 11 (req: > 3)
Antibodies: 203 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0