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Tdark
DZANK1
Double zinc ribbon and ankyrin repeat-containing protein 1

Protein Summary
Description
This gene contains two ankyrin repeat-encoding regions. Ankyrin repeats are tandemly repeated modules of about 33 amino acids described as L-shaped structures consisting of a beta-hairpin and two alpha-helices. Ankyrin repeats occur in a large number of functionally diverse proteins, mainly from eukaryotes, and are known to function as protein-protein interaction domains. [provided by RefSeq, Dec 2018]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000262547
  • ENSP00000262547
  • ENSG00000089091
  • ENST00000358866
  • ENSP00000351734
  • ENST00000609267
  • ENSP00000477046

Symbol
  • C20orf12
  • C20orf84
  • ANKRD64
  • C20orf12
  • C20orf84
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.92
cellular component
0.75
tissue sample
0.66
small molecule perturbation
0.61
protein domain
0.58


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.26   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 25   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.26   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 25   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0