Tbio HAUS2 HAUS augmin-like complex subunit 2

Protein Summary

Description

Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. The protein encoded by this gene is a subunit of the augmin complex. The augmin complex plays a role in microtubule attachment to the kinetochore and central spindle formation. [provided by RefSeq, Apr 2016]

Uniprot Accession IDs

• Q9NVX0
• C9JH36
• Q9H9B3

Gene Name

• HAUS2

Ensembl ID

• ENST00000260372
• ENSP00000260372
• ENSG00000137814
• ENST00000568876
• ENSP00000456578

Symbol

• C15orf25
• CEP27
• CEP27
• C15orf25
• HsT17025

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.95
histone modification site profile	0.88
transcription factor perturbation	0.74
cellular component	0.69
transcription factor binding site profile	0.68

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.36   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 61   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.36   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0