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Tbio
LILRA1
Leukocyte immunoglobulin-like receptor subfamily A member 1

Protein Summary
Description
May act as receptor for class I MHC antigens. This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000251372
  • ENSP00000251372
  • ENSG00000104974
  • ENST00000453777
  • ENSP00000413715
  • ENST00000617170
  • ENSP00000477637
  • ENSG00000275525
  • ENST00000620606
  • ENSP00000478666
  • ENST00000628480
  • ENSP00000487229
  • ENSG00000277398
  • ENST00000631007
  • ENSP00000487011
  • ENSG00000274935

Symbol
  • LIR6
  • LIR6
  • CD85I
  • LIR-6
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
1
tissue sample
0.73
cell line
0.65
cell type or tissue
0.62
protein domain
0.58


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.19   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 175   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.19   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 175   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0