Tbio STATH Statherin

Protein Summary

Description

Salivary protein that stabilizes saliva supersaturated with calcium salts by inhibiting the precipitation of calcium phosphate salts. It also modulates hydroxyapatite crystal formation on the tooth surface.

Uniprot Accession IDs

• P02808
• A6NKE9
• B2R4F8

Gene Name

• STATH

Ensembl ID

• ENST00000246895
• ENSP00000246895
• ENSG00000126549
• ENST00000381060
• ENSP00000370448
• ENST00000615994
• ENSP00000484341
• ENST00000634727
• ENSP00000489107
• ENSG00000282891
• ENST00000635437
• ENSP00000489569
• ENST00000635686
• ENSP00000489243

Symbol

• STR

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.58
cell line	0.5
metabolite	0.45
chemical	0.41
protein complex	0.4

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 249.36   (req: < 5)

Gene RIFs: 12   (req: <= 3)

Antibodies: 57   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 249.36   (req: >= 5)

Gene RIFs: 12   (req: > 3)

Antibodies: 57   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0