You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
MAZ
Myc-associated zinc finger protein

Protein Summary
Description
May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000219782
  • ENSP00000219782
  • ENSG00000103495
  • ENST00000322945
  • ENSP00000313362
  • ENST00000545521
  • ENSP00000443956
  • ENST00000562337
  • ENSP00000455726

Symbol
  • ZNF801
  • PUR1
  • ZF87
  • Pur-1
  • SAF-1
  • SAF-2
  • SAF-3
  • Zif87
  • ZNF801
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.88
transcription factor binding site profile
0.83
transcription factor
0.82
cell type or tissue
0.79
microRNA
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 279.41   (req: < 5)
Gene RIFs: 35   (req: <= 3)
Antibodies: 282   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 279.41   (req: >= 5)
Gene RIFs: 35   (req: > 3)
Antibodies: 282   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0