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Tbio
DHRS7
Dehydrogenase/reductase SDR family member 7

Protein Summary
Description
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family, which has over 46,000 members. Members in this family are enzymes that metabolize many different compounds, such as steroid hormones, prostaglandins, retinoids, lipids and xenobiotics. [provided by RefSeq, Apr 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000216500
  • ENSP00000216500
  • ENSG00000100612
  • ENST00000536410
  • ENSP00000442993
  • ENST00000557185
  • ENSP00000451882

Symbol
  • DHRS7A
  • RETSDR4
  • SDR34C1
  • CGI-86
  • SDR34C1
  • retDSR4
  • retSDR4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
pathway
0.95
virus perturbation
0.92
disease perturbation
0.9
transcription factor perturbation
0.8
histone modification site profile
0.77


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.1   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 221   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.1   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 221   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0