| Tdark | EMILIN-2 |
May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| lung carcinoma | 2843 | 7.8e-18 |
| malignant mesothelioma | 3232 | 3.1e-08 |
| ovarian cancer | 8520 | 4.4e-07 |
| ulcerative colitis | 1819 | 4.6e-07 |
| cystic fibrosis | 1696 | 4.7e-07 |
| Astrocytoma, Pilocytic | 3081 | 1.0e-05 |
| glioblastoma | 5792 | 2.1e-05 |
| osteosarcoma | 7950 | 8.7e-04 |
| adult high grade glioma | 3801 | 9.3e-04 |
| lung cancer | 4740 | 2.0e-03 |
| psoriasis | 6694 | 2.1e-03 |
| breast carcinoma | 1638 | 3.9e-03 |
| medulloblastoma, large-cell | 6241 | 5.2e-03 |
| invasive ductal carcinoma | 2951 | 9.6e-03 |
| primary pancreatic ductal adenocarcinoma | 1109 | 1.2e-02 |
| pancreatic carcinoma | 562 | 1.6e-02 |
| pancreatic cancer | 2398 | 1.6e-02 |
| pituitary cancer | 1972 | 1.7e-02 |
| gastric cancer | 459 | 2.1e-02 |
| subependymal giant cell astrocytoma | 2287 | 2.3e-02 |
| fibroadenoma | 559 | 2.5e-02 |
| COPD | 118 | 2.9e-02 |
| Breast cancer | 3578 | 4.6e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Rheumatoid arthritis | 1191 | 0.0 | 0.9 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | 1.600 | 9.3e-04 |
| Astrocytoma, Pilocytic | 1.900 | 1.0e-05 |
| Breast cancer | -1.400 | 4.6e-02 |
| breast carcinoma | -1.100 | 3.9e-03 |
| COPD | -1.100 | 2.9e-02 |
| cystic fibrosis | -2.571 | 4.7e-07 |
| fibroadenoma | -1.300 | 2.5e-02 |
| gastric cancer | -1.200 | 2.1e-02 |
| glioblastoma | 1.500 | 2.1e-05 |
| invasive ductal carcinoma | -1.200 | 9.6e-03 |
| lung cancer | -1.500 | 2.0e-03 |
| lung carcinoma | -1.300 | 7.8e-18 |
| malignant mesothelioma | 2.300 | 3.1e-08 |
| medulloblastoma, large-cell | 1.300 | 5.2e-03 |
| osteosarcoma | -1.499 | 8.7e-04 |
| ovarian cancer | -2.400 | 4.4e-07 |
| pancreatic cancer | -1.300 | 1.6e-02 |
| pancreatic carcinoma | -1.300 | 1.6e-02 |
| pituitary cancer | 1.500 | 1.7e-02 |
| primary pancreatic ductal adenocarcinoma | 1.137 | 1.2e-02 |
| psoriasis | -1.200 | 2.1e-03 |
| subependymal giant cell astrocytoma | 3.822 | 2.3e-02 |
| ulcerative colitis | 1.500 | 4.6e-07 |
| Species | Source | Disease |
|---|---|---|
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG |
MWQPRRPWPRVPWRWALALLALVGAGLCHAGPQPGYPARPSARNKNWCAYIVNKNVSCSVLEGSESFIQA 1 - 70 QYNCAWNQMPCPSALVYRVNFRPRYVTRYKTVTQLEWRCCPGFRGGDCQEGPKDPVKTLRPTPARPRNSL 71 - 140 KKATDNEPSQFSEPRKTLSPTGTAQPSWGVDPKEGPQELQEKKIQVLEEKVLRLTRTVLDLQSSLAGVSE 141 - 210 NLKHATQDDASRTRAPGLSSQHPKPDTTVSGDTETGQSPGVFNTKESGMKDIKSELAEVKDTLKNKSDKL 211 - 280 EELDGKVKGYEGQLRQLQEAAQGPTVTMTTNELYQAYVDSKIDALREELMEGMDRKLADLKNSCEYKLTG 281 - 350 LQQQCDDYGSSYLGVIELIGEKETSLRKEINNLRARLQEPSAQANCCDSEKNGDIGQQIKTLDQKIERVA 351 - 420 EATRMLNGRLDNEFDRLIVPEPDVDFDAKWNELDARINVTEKNAEEHCFYIEETLRGAINGEVGDLKQLV 421 - 490 DQKIQSLEDRLGSVLLQMTNNTGAELSPPGAAALPGVSGSGDERVMMELNHLKDKVQVVEDICLLNIQGK 491 - 560 PHGMEGALPNREDRAVRDSLHLLKSLNDTMHRKFQETEQTIQKLQQDFSFLYSQLNHTENDVTHLQKEMS 561 - 630 NCRAGENAGMGRFTKVGEQERTVDTLPSPQHPVAHCCSQLEERWQRLQSQVISELDACKECTQGVQREVS 631 - 700 MVEGRVSHMEKTCSKLDSISGNLQRIKEGLNKHVSSLWNCVRQMNGTLRSHSRDISGLKNSVQQFYSHVF 701 - 770 QISTDLQDLVKFQPSAKAPSPPPPAEAPKEPLQPEPAPPRPSGPATAEDPGRRPVLPQRPPEERPPQPPG 771 - 840 STGVIAETGQAGPPAGAGVSGRGLPRGVDGQTGSGTVPGAEGFAGAPGYPKSPPVASPGAPVPSLVSFSA 841 - 910 GLTQKPFPSDGGVVLFNKVLVNDGDVYNPSTGVFTAPYDGRYLITATLTPERDAYVEAVLSVSNASVAQL 911 - 980 HTAGYRREFLEYHRPPGALHTCGGPGAFHLIVHLKAGDAVNVVVTGGKLAHTDFDEMYSTFSGVFLYPFL 981 - 1050 SHL 1051 - 1053 //
