Protein Summary
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
- ENST00000611323
- ENSP00000479069
- ENSG00000278674
- TCEB3CL
- ELOA3
- EloA3C
- HsT828
- TCEB3C
- ELOA3L1
- TCEB3CL
- TCEB3L2
- Elongin-A3
- eloA3-like-1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
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biological process | 0 | ||
biological term | 0 | ||
cell line | 0 | ||
cell type or tissue | 0 | ||
cellular component | 0 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.19 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 1 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.19 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 1 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0