| Tbio | ELMO domain-containing protein 1 |
Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| periodontitis | 293 | 1.5e-22 |
| psoriasis | 6694 | 6.4e-15 |
| atypical teratoid / rhabdoid tumor | 5112 | 1.2e-07 |
| group 3 medulloblastoma | 4104 | 3.2e-06 |
| Astrocytoma, Pilocytic | 3081 | 5.3e-06 |
| medulloblastoma, large-cell | 6241 | 3.1e-05 |
| glioblastoma | 5792 | 3.5e-05 |
| Atopic dermatitis | 952 | 4.3e-05 |
| adult high grade glioma | 3801 | 6.5e-05 |
| primitive neuroectodermal tumor | 3035 | 1.4e-02 |
| aldosterone-producing adenoma | 665 | 1.9e-02 |
| osteosarcoma | 7950 | 2.1e-02 |
| astrocytic glioma | 2597 | 2.2e-02 |
| Pick disease | 1894 | 2.4e-02 |
| ependymoma | 4679 | 3.2e-02 |
| oligodendroglioma | 2850 | 3.3e-02 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -2.300 | 6.5e-05 |
| aldosterone-producing adenoma | -1.470 | 1.9e-02 |
| astrocytic glioma | -2.200 | 2.2e-02 |
| Astrocytoma, Pilocytic | -1.300 | 5.3e-06 |
| Atopic dermatitis | -2.800 | 4.3e-05 |
| atypical teratoid / rhabdoid tumor | -5.200 | 1.2e-07 |
| ependymoma | -1.300 | 3.2e-02 |
| glioblastoma | -2.400 | 3.5e-05 |
| group 3 medulloblastoma | -4.300 | 3.2e-06 |
| medulloblastoma, large-cell | -4.100 | 3.1e-05 |
| oligodendroglioma | -1.600 | 3.3e-02 |
| osteosarcoma | 1.615 | 2.1e-02 |
| periodontitis | -1.400 | 1.5e-22 |
| Pick disease | -1.900 | 2.4e-02 |
| primitive neuroectodermal tumor | -2.500 | 1.4e-02 |
| psoriasis | -1.400 | 6.4e-15 |
MKHFLRMLIQVCLYFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSV 1 - 70 SVHPDAIEKTIEDIMELKKINPDVNPQLGISLQACLLQIVGYRNLIADVEKLRREAYDSDNPQHEEMLLK 71 - 140 LWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDATAAQQVLSDSLHPKCRDI 141 - 210 TKEEISKFSKAEWEKKRMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYL 211 - 280 MHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM 281 - 334 //
