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Tbio
EIF1
Eukaryotic translation initiation factor 1

Protein Summary
Description
Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000469257
  • ENSP00000419449
  • ENSG00000173812

Symbol
  • SUI1
  • A121
  • ISO1
  • SUI1
  • EIF-1
  • EIF1A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
1
transcription factor binding site profile
0.97
disease perturbation
0.96
transcription factor perturbation
0.94
PubMedID
0.7


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 216.59   (req: < 5)
Gene RIFs: 11   (req: <= 3)
Antibodies: 180   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 216.59   (req: >= 5)
Gene RIFs: 11   (req: > 3)
Antibodies: 180   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0