Tbio EEF1G Elongation factor 1-gamma

Protein Summary

Description

Probably plays a role in anchoring the complex to other cellular components. This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• P26641
• B4DTG2
• Q6PJ62
• Q6PK31
• Q96CU2
• Q9P196
• EF-1-gamma

Gene Name

• EEF1G

Ensembl ID

• ENST00000329251
• ENSP00000331901
• ENSG00000254772

Symbol

• EF1G
• EF1G
• GIG35

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
interacting protein	1
small molecule perturbation	1
disease perturbation	0.96
kinase perturbation	0.95
hub protein	0.92

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 70.08   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 333   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 70.08   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 333   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0