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Tbio
EEF1B2
Elongation factor 1-beta

Protein Summary
Description
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP. This gene encodes a translation elongation factor. The protein is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome. Alternative splicing results in three transcript variants which differ only in the 5' UTR. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000236957
  • ENSP00000236957
  • ENSG00000114942
  • ENST00000392221
  • ENSP00000376055
  • ENST00000392222
  • ENSP00000376056
  • ENST00000635728
  • ENSP00000489993
  • ENSG00000283391
  • ENST00000636275
  • ENSP00000490326
  • ENST00000637253
  • ENSP00000490214

Symbol
  • EEF1B
  • EF1B
  • EF1B
  • EEF1B
  • EEF1B1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
1
drug perturbation
0.96
ligand (protein) perturbation
0.96
disease perturbation
0.95
hub protein
0.92


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 104.94   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 179   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 104.94   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 179   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0