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Tdark EEF1A lysine methyltransferase 1

Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.

 Comments

Property Summary

NCBI Gene PubMed Count 8
PubMed Score 2.00
PubTator Score 0.25

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (3)

Disease Target Count P-value
medulloblastoma, large-cell 6241 5.7e-03
acute myeloid leukemia 783 2.7e-02
Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 0.5
Disease Target Count Z-score Confidence
Otitis Media 52 3.036 1.5

Expression

  Differential Expression (2)

Disease log2 FC p
acute myeloid leukemia -3.100 2.7e-02
medulloblastoma, large-cell -1.100 5.7e-03

Synonym

Accession Q8WVE0 B5G4V1
Symbols ESP13
N6AMT2

Gene

EEF1AKMT1

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

 UniProt Keyword (8)

 GO Function (3)

 GO Component (2)

 GO Process (2)

 Compartment GO Term (9)

 MGI Phenotype (1)

 HCA RNA Cell Line (55)

See all...

Protein-protein Interaction (5)

EGLN1   EEF1A2   EEF1A1   TTLL12   NFS1  

Gene RIF (1)

AA Sequence 

MSDLEDDETPQLSAHALAALQEFYAEQKQQIEPGEDDKYNIGIIEENWQLSQFWYSQETALQLAQEAIAA      1 - 70
VGEGGRIACVSAPSVYQKLRELCRENFSIYIFEYDKRFAMYGEEFIFYDYNNPLDLPERIAAHSFDIVIA     71 - 140
DPPYLSEECLRKTSETVKYLTRGKILLCTGAIMEEQAAELLGVKMCTFVPRHTRNLANEFRCYVNYDSGL    141 - 210
DCGI                                                                      211 - 214
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Text Mined References (12)

PMID Year Title