Property Summary

NCBI Gene PubMed Count 16
PubMed Score 5.31
PubTator Score 7.62

Knowledge Summary


No data available


  Disease (1)


  Differential Expression (3)

Disease log2 FC p
medulloblastoma, large-cell 1.100 1.2e-04
adult high grade glioma 1.100 2.5e-04
ovarian cancer 2.000 2.0e-05

Gene RIF (7)

25258324 The state of DUE-B phosphorylation is maintained by the equilibrium between Cdc7-dependent phosphorylation and PP2A-dependent dephosphorylation.
24772479 LDI-PCR revealed a fusion between DTD1 exon 4 and PDGFRB exon 12 in the cases with t(5;14)(q33;q32) and t(5;20)(q33;p11).
21479357 DTD1 variants do not affect the abnormalities of the upper airways in aspirin-intolerant asthma patients
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
20065034 The coordinated binding of DUE-B and Cdc45 to origins and the physical interactions of DUE-B, Cdc45, and TopBP1 suggest that complexes of these proteins are necessary for replication initiation.
15653697 DUE-B, a c-myc DNA-unwinding element-binding protein, plays an important role in replication in vivo.
12392168 cloning and identification of novel cDNA which may be associated with FKBP25

AA Sequence


Text Mined References (26)

PMID Year Title
25258324 2014 Protein phosphatase 2A and Cdc7 kinase regulate the DNA unwinding element-binding protein in replication initiation.
24772479 2014 Identification and functional characterization of imatinib-sensitive DTD1-PDGFRB and CCDC88C-PDGFRB fusion genes in eosinophilia-associated myeloid/lymphoid neoplasms.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
22814378 2012 N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
21479357 2011 Association analysis of DTD1 gene variations with aspirin-intolerance in asthmatics.
21406692 2011 System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
21269460 2011 Initial characterization of the human central proteome.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
20068231 2010 Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
20065034 2010 The DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation.
19690332 2009 Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
19413330 2009 Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
18669648 2008 A quantitative atlas of mitotic phosphorylation.
18088087 2008 Phosphoproteome of resting human platelets.
18029348 2008 Toward a confocal subcellular atlas of the human proteome.
17264083 2007 Structure and function of the c-myc DNA-unwinding element-binding protein DUE-B.
17207965 2007 hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
15910003 2005 Ku80 binds to human replication origins prior to the assembly of the ORC complex.
15653697 2005 The c-myc DNA-unwinding element-binding protein modulates the assembly of DNA replication complexes in vitro.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12392168 2002 Cloning and identification of a novel cDNA which may be associated with FKBP25.
11780052 2001 The DNA sequence and comparative analysis of human chromosome 20.
8889548 1996 Normalization and subtraction: two approaches to facilitate gene discovery.