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Tbio
DLGAP3
Disks large-associated protein 3

Protein Summary
Description
May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000235180
  • ENSP00000235180
  • ENSG00000116544
  • ENST00000373347
  • ENSP00000362444

Symbol
  • DAP3
  • DAP3
  • SAPAP3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.68
hub protein
0.67
PubMedID
0.61
cell line
0.49
tissue sample
0.44


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 69.69   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 109   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 69.69   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 109   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0