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  6. Putative ATP-dependent RNA helicase DHX57

Tdark Putative ATP-dependent RNA helicase DHX57

Probable ATP-binding RNA helicase.

 Comments

Property Summary

NCBI Gene PubMed Count 13
PubMed Score 0.58
PubTator Score 0.58

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (2)

Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 1.0
Kidney cancer 2613 0.0 0.7

Expression

  Differential Expression (7)

Disease log2 FC p
ependymoma 1.200 1.6e-02
intraductal papillary-mucinous adenoma (... 1.300 1.3e-03
intraductal papillary-mucinous carcinoma... 1.100 1.5e-02
lung cancer 1.100 1.8e-03
oligodendroglioma 1.100 2.0e-03
ovarian cancer -1.500 2.4e-07
tuberculosis and treatment for 6 months 1.100 5.7e-04

Synonym

Accession Q6P158 A2RRC7 Q53SI4 Q6P9G1 Q7Z6H3 Q8NG17 Q96M33
Symbols DDX57

Gene

DHX57

PANTHER Protein Class (3)

  Ortholog (1)

Species Source Disease
Macaque OMA Inparanoid

 UniProt Keyword (13)

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 GO Function (4)

 GO Component (1)

 GO Process (1)

 Compartment GO Term (17)

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 GWAS Trait (1)

 HCA RNA Cell Line (56)

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Protein-protein Interaction (16)

UBB   RPS14   HSPA8   ACTBL2   HIST1H1E   RPS2   ZDHHC17   MUCL1   SRC   CLU   EEF1A2   RPSA   TTLL12   APOD   GLMN   SESN2  

AA Sequence 

MSSSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDDGDDFCIFSES      1 - 70
RRPSRPSNSNISKGESRPKWKPKAKVPLQTLHMTSENQEKVKALLRDLQEQDADAGSERGLSGEEEDDEP     71 - 140
DCCNDERYWPAGQEPSLVPDLDPLEYAGLASVEPYVPEFTVSPFAVQKLSRYGFNTERCQAVLRMCDGDV    141 - 210
GASLEHLLTQCFSETFGERMKISEAVNQISLDECMEQRQEEAFALKSICGEKFIERIQNRVWTIGLELEY    211 - 280
LTSRFRKSKPKESTKNVQENSLEICKFYLKGNCKFGSKCRFKHEVPPNQIVGRIERSVDDSHLNAIEDAS    281 - 350
FLYELEIRFSKDHKYPYQAPLVAFYSTNENLPLACRLHISEFLYDKALTFAETSEPVVYSLITLLEEESE    351 - 420
IVKLLTNTHHKYSDPPVNFLPVPSRTRINNPACHKTVIPNNSFVSNQIPEVEKASESEESDEDDGPAPVI    421 - 490
VENESYVNLKKKISKRYDWQAKSVHAENGKICKQFRMKQASRQFQSILQERQSLPAWEERETILNLLRKH    491 - 560
QVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIR    561 - 630
LESVKSSATRLLYCTTGVLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMS    631 - 700
ATLNAELFSDYFNSCPVITIPGRTFPVDQFFLEDAIAVTRYVLQDGSPYMRSMKQISKEKLKARRNRTAF    701 - 770
EEVEEDLRLSLHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIKTMSIMDFEKVNLELIEALLEWIVD    771 - 840
GKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKII    841 - 910
ISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSH    911 - 980
HYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDE    981 - 1050
RLTPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSD   1051 - 1120
YLALLQAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEKRAQ   1121 - 1190
GGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQPKSAELKFVTKNDG   1191 - 1260
YVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMVSVYPLVLFGGGQVNVQLQRGEFVVSLDDGW   1261 - 1330
IRFVAASHQVAELVKELRCELDQLLQDKIKNPSIDLCTCPRGSRIISTIVKLVTTQ                 1331 - 1386
//

Text Mined References (19)

PMID Year Title