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  6. Putative ATP-dependent RNA helicase DHX57

Tdark Putative ATP-dependent RNA helicase DHX57

Probable ATP-binding RNA helicase.

 Comments

Property Summary

NCBI Gene PubMed Count 13
PubMed Score 0.58
PubTator Score 0.58

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (2)

Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 1.0
Kidney cancer 2613 0.0 0.7

Expression

  Differential Expression (7)

Disease log2 FC p
ependymoma 1.200 1.6e-02
intraductal papillary-mucinous adenoma (... 1.300 1.3e-03
intraductal papillary-mucinous carcinoma... 1.100 1.5e-02
lung cancer 1.100 1.8e-03
oligodendroglioma 1.100 2.0e-03
ovarian cancer -1.500 2.4e-07
tuberculosis and treatment for 6 months 1.100 5.7e-04

Synonym

Accession Q6P158 A2RRC7 Q53SI4 Q6P9G1 Q7Z6H3 Q8NG17 Q96M33
Symbols DDX57

Gene

DHX57

PANTHER Protein Class (3)

  Ortholog (9)

Species Source Disease
Inparanoid OMA
Inparanoid OMA
Inparanoid OMA
Inparanoid OMA
Inparanoid OMA
Inparanoid OMA
Inparanoid OMA
Inparanoid OMA
Inparanoid OMA

 UniProt Keyword (13)

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 GO Function (4)

 GO Component (1)

 GO Process (1)

 Compartment GO Term (17)

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 GWAS Trait (1)

 HCA RNA Cell Line (56)

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Protein-protein Interaction (16)

UBB   RPS14   HSPA8   ACTBL2   HIST1H1E   RPS2   ZDHHC17   MUCL1   SRC   CLU   EEF1A2   RPSA   TTLL12   APOD   GLMN   SESN2  

AA Sequence 

MSSSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDDGDDFCIFSES      1 - 70
RRPSRPSNSNISKGESRPKWKPKAKVPLQTLHMTSENQEKVKALLRDLQEQDADAGSERGLSGEEEDDEP     71 - 140
DCCNDERYWPAGQEPSLVPDLDPLEYAGLASVEPYVPEFTVSPFAVQKLSRYGFNTERCQAVLRMCDGDV    141 - 210
GASLEHLLTQCFSETFGERMKISEAVNQISLDECMEQRQEEAFALKSICGEKFIERIQNRVWTIGLELEY    211 - 280
LTSRFRKSKPKESTKNVQENSLEICKFYLKGNCKFGSKCRFKHEVPPNQIVGRIERSVDDSHLNAIEDAS    281 - 350
FLYELEIRFSKDHKYPYQAPLVAFYSTNENLPLACRLHISEFLYDKALTFAETSEPVVYSLITLLEEESE    351 - 420
IVKLLTNTHHKYSDPPVNFLPVPSRTRINNPACHKTVIPNNSFVSNQIPEVEKASESEESDEDDGPAPVI    421 - 490
VENESYVNLKKKISKRYDWQAKSVHAENGKICKQFRMKQASRQFQSILQERQSLPAWEERETILNLLRKH    491 - 560
QVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIR    561 - 630
LESVKSSATRLLYCTTGVLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMS    631 - 700
ATLNAELFSDYFNSCPVITIPGRTFPVDQFFLEDAIAVTRYVLQDGSPYMRSMKQISKEKLKARRNRTAF    701 - 770
EEVEEDLRLSLHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIKTMSIMDFEKVNLELIEALLEWIVD    771 - 840
GKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKII    841 - 910
ISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSH    911 - 980
HYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDE    981 - 1050
RLTPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSD   1051 - 1120
YLALLQAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEKRAQ   1121 - 1190
GGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQPKSAELKFVTKNDG   1191 - 1260
YVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMVSVYPLVLFGGGQVNVQLQRGEFVVSLDDGW   1261 - 1330
IRFVAASHQVAELVKELRCELDQLLQDKIKNPSIDLCTCPRGSRIISTIVKLVTTQ                 1331 - 1386
//

Text Mined References (19)

PMID Year Title