Tdark DCDC2B Doublecortin domain-containing protein 2B

Protein Summary

Description

This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. [provided by RefSeq, Sep 2010]

Uniprot Accession IDs

• A2VCK2
• B7ZBC6

Gene Name

• DCDC2B

Ensembl ID

• ENST00000409358
• ENSP00000386870
• ENSG00000222046

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cellular component	0.95
tissue sample	0.66
tissue	0.52
cell line	0.44
transcription factor	0.31

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 32   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 32   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0