| Tdark | DDB1- and CUL4-associated factor 10 |
May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| malignant mesothelioma | 3232 | 6.3e-06 |
| osteosarcoma | 7950 | 3.3e-03 |
| lung cancer | 4740 | 7.3e-03 |
| pancreatic ductal adenocarcinoma liver metastasis | 1962 | 1.1e-02 |
| subependymal giant cell astrocytoma | 2287 | 4.0e-02 |
| Disease | log2 FC | p |
|---|---|---|
| lung cancer | -1.200 | 7.3e-03 |
| malignant mesothelioma | 1.300 | 6.3e-06 |
| osteosarcoma | -1.052 | 3.3e-03 |
| pancreatic ductal adenocarcinoma liver m... | -1.626 | 1.1e-02 |
| subependymal giant cell astrocytoma | -1.064 | 4.0e-02 |
MFPFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSLSPAPRSGE 1 - 70 LGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPGARLFGWLKERSLGRGLFVDP 71 - 140 ARDNFRTMTSLYGSIHPADSVYLSTRTHGAVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAH 141 - 210 EDCVNNIRFLDNRLFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIW 211 - 280 DTNRYTEDGCPHKKFFHTRFLMRMRLTPDCSKMLISTSSGYLLILHDLDLTKSLEVGSYPILRARRTTSS 281 - 350 SDLTTSSSSSGPRVSGSPCHHSDSNSSEKHMSRASQREGVSPRNSLEVVTPEVLGESDHGNCITSLQLHP 351 - 420 KGWATLLRCSSNSDDEECTCVYEFQEGAPVRPVSPRCSLRLTHYIEEANVGRGYIKELCFSPDGRMISSP 421 - 490 HGYGIRLLGFDKQCSELVDCLPKEASPLRVIRSLYSHNDVVLTTKFSPTHCQIASGCLSGRVSLYQPKF 491 - 559 //
