Protein Summary
Possible architectural role during spermatogenesis. May be involved in spermatid differentiation. Cylicin II (CYCL2) is specifically expressed in testis and is part of the cytoskeletal calyx of mammalian sperm heads. Cylicin II may play a role in the morphogenesis of the sperm head. [provided by RefSeq, Jul 2008]
- ENST00000374798
- ENSP00000420256
- ENSG00000155833
- ENST00000487798
- ENSP00000417674
- ENST00000612124
- ENSP00000478399
- CYL2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.58 | ||
disease | 0.48 | ||
kinase perturbation | 0.42 | ||
phenotype | 0.41 | ||
cell line | 0.4 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 15.19 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 70 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 15.19 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 70 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0