| Tbio | C-X-C motif chemokine 16 |
Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Liver Cirrhosis, Experimental | 769 | 0.0 | 0.0 |
| Disease | Target Count | P-value |
|---|---|---|
| lung carcinoma | 2843 | 9.5e-18 |
| non-small cell lung cancer | 2890 | 1.1e-14 |
| Astrocytoma, Pilocytic | 3081 | 1.8e-08 |
| posterior fossa group A ependymoma | 468 | 1.4e-07 |
| ovarian cancer | 8520 | 3.8e-07 |
| glioblastoma | 5792 | 1.7e-04 |
| tuberculosis | 2010 | 1.9e-04 |
| active ulcerative colitis | 764 | 3.3e-03 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2989 | 4.3e-03 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 1.0e-02 |
| adult high grade glioma | 3801 | 1.2e-02 |
| pancreatic cancer | 2398 | 1.8e-02 |
| group 3 medulloblastoma | 4104 | 1.8e-02 |
| primary pancreatic ductal adenocarcinoma | 1109 | 2.7e-02 |
| osteosarcoma | 7950 | 4.2e-02 |
| Disease | log2 FC | p |
|---|---|---|
| active ulcerative colitis | 2.452 | 3.3e-03 |
| adult high grade glioma | 1.500 | 1.2e-02 |
| Astrocytoma, Pilocytic | 1.900 | 1.8e-08 |
| glioblastoma | 1.300 | 1.7e-04 |
| group 3 medulloblastoma | -1.100 | 1.8e-02 |
| intraductal papillary-mucinous carcinoma... | 2.200 | 4.3e-03 |
| intraductal papillary-mucinous neoplasm ... | 2.400 | 1.0e-02 |
| lung carcinoma | -2.500 | 9.5e-18 |
| non-small cell lung cancer | -1.452 | 1.1e-14 |
| osteosarcoma | -1.273 | 4.2e-02 |
| ovarian cancer | 2.700 | 3.8e-07 |
| pancreatic cancer | 1.600 | 1.8e-02 |
| posterior fossa group A ependymoma | 1.300 | 1.4e-07 |
| primary pancreatic ductal adenocarcinoma | 1.443 | 2.7e-02 |
| tuberculosis | -1.900 | 1.9e-04 |
