Tbio CSTF2T Cleavage stimulation factor subunit 2 tau variant

Protein Summary

Description

May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Directly involved in the binding to pre-mRNAs (By similarity).

Uniprot Accession IDs

• Q9H0L4
• B2RAR9
• O75174
• Q53HK6
• Q7LGE8
• Q8N6T1

Gene Name

• CSTF2T

Ensembl ID

• ENST00000331173
• ENSP00000332444
• ENSG00000177613

Symbol

• KIAA0689
• CstF-64T

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.93
disease perturbation	0.9
virus perturbation	0.9
transcription factor binding site profile	0.88
histone modification site profile	0.8

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Mrna Processing Factor / Mrna Splicing Factor / Cleavage Stimulation Factor Subunit 2 Tau Variant

DTO Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Mrna Processing Factor / Mrna Splicing Factor / Cleavage Stimulation Factor Subunit 2 Tau Variant

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.56   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 179   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.56   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 179   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0