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Tbio
CSF3
Granulocyte colony-stimulating factor

Protein Summary
Description
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000225474
  • ENSP00000225474
  • ENSG00000108342
  • ENST00000394148
  • ENSP00000377704
  • ENST00000394149
  • ENSP00000377705

Symbol
  • C17orf33
  • GCSF
  • GCSF
  • CSF3OS
  • C17orf33
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0.98
biological term
0.94
gene perturbation
0.88
disease
0.86
cell type or tissue
0.77


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10692.88   (req: < 5)
Gene RIFs: 169   (req: <= 3)
Antibodies: 1146   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10692.88   (req: >= 5)
Gene RIFs: 169   (req: > 3)
Antibodies: 1146   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 23
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0