| Tbio | Quinone oxidoreductase-like protein 1 |
This gene encodes a protein that has sequence similarity to zeta crystallin, also known as quinone oxidoreductase. This zeta crystallin-like protein also contains an NAD(P)H binding site. Alternatively spliced transcript variants have been observed but their full-length nature has not been completely determined. [provided by RefSeq, Jul 2008]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| ovarian cancer | 8520 | 6.0e-15 |
| medulloblastoma, large-cell | 6241 | 1.6e-04 |
| adult high grade glioma | 3801 | 3.3e-04 |
| osteosarcoma | 7950 | 8.9e-04 |
| glioblastoma | 5792 | 1.1e-03 |
| astrocytoma | 1146 | 3.6e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| FG syndrome | 16 | 5.043 | 2.5 |
| Norrie disease | 14 | 4.956 | 2.5 |
| Exudative vitreoretinopathy | 15 | 4.041 | 2.0 |
| Opitz-GBBB syndrome | 18 | 3.415 | 1.7 |
| Congenital stationary night blindness | 29 | 3.34 | 1.7 |
| Coats disease | 13 | 3.178 | 1.6 |
| Intellectual disability | 1016 | 3.153 | 1.6 |
| Congenital nystagmus | 26 | 3.01 | 1.5 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -1.700 | 3.3e-04 |
| astrocytoma | -1.100 | 3.6e-02 |
| glioblastoma | -1.600 | 1.1e-03 |
| medulloblastoma, large-cell | -1.300 | 1.6e-04 |
| osteosarcoma | 1.344 | 8.9e-04 |
| ovarian cancer | -2.200 | 6.0e-15 |
MKGLYFQQSSTDEEITFVFQEKEDLPVTEDNFVKLQVKACALSQINTKLLAEMKMKKDLFPVGREIAGIV 1 - 70 LDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVRAYTALHYLS 71 - 140 HLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDKQCLERFRPPIARVIDVSNGKVHVAESCL 141 - 210 EETGGLGVDIVLDAGVRLYSKDDEPAVKLQLLPHKHDIITLLGVGGHWVTTEENLQLDPPDSHCLFLKGA 211 - 280 TLAFLNDEVWNLSNVQQGKYLCILKDVMEKLSTGVFRPQLDEPIPLYEAKVSMEAVQKNQGRKKQVVQF 281 - 349 //
