| Tbio | Cholinephosphotransferase 1 |
Catalyzes phosphatidylcholine biosynthesis from CDP-choline. It thereby plays a central role in the formation and maintenance of vesicular membranes.
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Respiratory Distress Syndrome, Adult | 40 | 0.0 | 0.0 |
| Disease | Target Count | P-value |
|---|---|---|
| lung carcinoma | 2843 | 1.1e-23 |
| non-small cell lung cancer | 2890 | 2.4e-12 |
| psoriasis | 6694 | 1.3e-09 |
| lung adenocarcinoma | 2716 | 2.0e-09 |
| ulcerative colitis | 1819 | 6.2e-06 |
| group 3 medulloblastoma | 4104 | 5.5e-05 |
| Breast cancer | 3578 | 1.7e-04 |
| interstitial cystitis | 2312 | 6.4e-04 |
| atypical teratoid / rhabdoid tumor | 5112 | 6.6e-04 |
| medulloblastoma, large-cell | 6241 | 1.9e-03 |
| osteosarcoma | 7950 | 3.9e-03 |
| Waldenstrons macroglobulinemia | 765 | 5.6e-03 |
| intraductal papillary-mucinous adenoma (IPMA) | 2955 | 7.4e-03 |
| aldosterone-producing adenoma | 665 | 1.2e-02 |
| Rheumatoid arthritis | 1191 | 1.8e-02 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 2.3e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Newborn respiratory distress syndrome | 10 | 4.042 | 2.0 |
| Disease | Target Count |
|---|---|
| Spermatogenesis arrest | 2 |
| Disease | log2 FC | p |
|---|---|---|
| aldosterone-producing adenoma | -1.552 | 1.2e-02 |
| atypical teratoid / rhabdoid tumor | -1.100 | 6.6e-04 |
| Breast cancer | -1.200 | 1.7e-04 |
| group 3 medulloblastoma | -1.700 | 5.5e-05 |
| interstitial cystitis | -1.300 | 6.4e-04 |
| intraductal papillary-mucinous adenoma (... | 1.500 | 7.4e-03 |
| intraductal papillary-mucinous neoplasm ... | 1.500 | 2.3e-02 |
| lung adenocarcinoma | -1.100 | 2.0e-09 |
| lung carcinoma | -1.600 | 1.1e-23 |
| medulloblastoma, large-cell | -1.500 | 1.9e-03 |
| non-small cell lung cancer | -1.126 | 2.4e-12 |
| osteosarcoma | -1.176 | 3.9e-03 |
| psoriasis | -1.800 | 1.3e-09 |
| Rheumatoid arthritis | 1.200 | 1.8e-02 |
| ulcerative colitis | -1.200 | 6.2e-06 |
| Waldenstrons macroglobulinemia | 1.153 | 5.6e-03 |
| Species | Source | Disease |
|---|---|---|
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA | ||
| OMA EggNOG | ||
| Inparanoid EggNOG | ||
| OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG |
MAAGAGAGSAPRWLRALSEPLSAAQLRRLEEHRYSAAGVSLLEPPLQLYWTWLLQWIPLWMAPNSITLLG 1 - 70 LAVNVVTTLVLISYCPTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLST 71 - 140 VFMAVGASIAARLGTYPDWFFFCSFIGMFVFYCAHWQTYVSGMLRFGKVDVTEIQIALVIVFVLSAFGGA 141 - 210 TMWDYTIPILEIKLKILPVLGFLGGVIFSCSNYFHVILHGGVGKNGSTIAGTSVLSPGLHIGLIIILAIM 211 - 280 IYKKSATDVFEKHPCLYILMFGCVFAKVSQKLVVAHMTKSELYLQDTVFLGPGLLFLDQYFNNFIDEYVV 281 - 350 LWMAMVISSFDMVIYFSALCLQISRHLHLNIFKTACHQAPEQVQVLSSKSHQNNMD 351 - 406 //
