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Tbio
CGRRF1
Cell growth regulator with RING finger domain protein 1

Protein Summary
Description
Able to inhibit growth in several cell lines.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000216420
  • ENSP00000216420
  • ENSG00000100532

Symbol
  • CGR19
  • RNF197
  • CGR19
  • RNF197
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.76
histone modification site profile
0.7
transcription factor binding site profile
0.68
tissue sample
0.59
gene perturbation
0.53


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.88   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 152   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.88   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 152   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0