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Tbio
CFAP20
Cilia- and flagella-associated protein 20

Protein Summary
Description
Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia (PubMed:24414207). Required for axonemal microtubules polyglutamylation (PubMed:24414207).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000262498
  • ENSP00000262498
  • ENSG00000070761

Symbol
  • BUG22
  • C16orf80
  • GTL3
  • GTL3
  • BUG22
  • EVORF
  • fSAP23
  • C16orf80
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.9
kinase perturbation
0.84
transcription factor
0.66
cellular component
0.64
cell type or tissue
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 57.63   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 109   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 57.63   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 109   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0