Property Summary

NCBI Gene PubMed Count 13
PubMed Score 54.83
PubTator Score 104.46

Knowledge Summary


No data available


  Disease (2)

Disease Target Count P-value
ovarian cancer 8491 1.2e-11
osteosarcoma 7933 1.2e-06
psoriasis 6685 6.2e-04


  Differential Expression (3)

Disease log2 FC p
psoriasis 1.400 6.2e-04
osteosarcoma 1.315 1.2e-06
ovarian cancer 1.200 1.2e-11

Gene RIF (3)

25261648 CETN1 is overexpressed in breast cancer tissue and promotes cells'proliferation, tumor growth and metastasis.
16760425 These data demonstrate a functional role for CaM binding to CP110 and suggest that CP110 cooperates with CaM and centrin to regulate progression through cytokinesis.
16101678 Studies using a combined approach of immunofluorescence detection of Gag protein and in situ hybridization detection of viral genomic RNA indicate Gag co-localizes with Psi+ RNA in the perinuclear region and also co-localizes with centrins

AA Sequence

ELQEMIDEADRDGDGEVNEEEFLRIMKKTSLY                                          141 - 172

Text Mined References (14)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
25261648 Knockdown of CETN1 inhibits breast cancer cells proliferation.
24421332 2014 The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly.
24252580 2013 CETN1 is a cancer testis antigen with expression in prostate and pancreatic cancers.
20643351 2010 Pitchfork regulates primary cilia disassembly and left-right asymmetry.
18331714 2008 sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1.
16760425 2006 CP110 cooperates with two calcium-binding proteins to regulate cytokinesis and genome stability.
16246726 2005 The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11279195 2001 Phosphorylation of centrin during the cell cycle and its role in centriole separation preceding centrosome duplication.
10725219 2000 Differential expression and cellular distribution of centrin isoforms during human ciliated cell differentiation in vitro.
8175926 1994 Cloning of a cDNA encoding human centrin, an EF-hand protein of centrosomes and mitotic spindle poles.