Tdark CEP126 Centrosomal protein of 126 kDa

Protein Summary

Description

Participates in cytokinesis (PubMed:19799413). Necessary for microtubules and mitotic spindle organization (PubMed:24867236). Involved in primary cilium formation (PubMed:24867236).

Uniprot Accession IDs

• Q9P2H0
• Q4G0U6

Gene Name

• CEP126

Ensembl ID

• ENST00000263468
• ENSP00000263468
• ENSG00000110318

Symbol

• KIAA1377
• KIAA1377

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.84
cell type or tissue	0.74
hub protein	0.67
cell line	0.58
transcription factor	0.58

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.75   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 27   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.75   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0