Property Summary

NCBI Gene PubMed Count 13
PubMed Score 2.06
PubTator Score 3.98

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (17)

Disease log2 FC p
astrocytic glioma -1.500 1.0e-02
glioblastoma -2.900 1.2e-05
osteosarcoma -1.645 3.7e-04
group 3 medulloblastoma -3.500 9.7e-07
atypical teratoid / rhabdoid tumor -2.900 9.0e-09
medulloblastoma, large-cell -3.900 6.1e-08
primitive neuroectodermal tumor -1.700 1.2e-03
non-small cell lung cancer -1.535 9.7e-13
adult high grade glioma -2.600 2.1e-05
pilocytic astrocytoma -1.300 4.9e-04
posterior fossa group B ependymoma 1.300 1.3e-03
lung carcinoma 1.300 2.1e-07
ductal carcinoma in situ -1.900 1.1e-03
invasive ductal carcinoma -1.700 4.1e-02
ovarian cancer -1.300 7.1e-04
chronic rhinosinusitis -1.769 1.6e-02
cystic fibrosis and chronic rhinosinusit... -1.096 3.9e-02

Gene RIF (2)

PMID Text
24867236 CEP126 is a regulator of microtubule organisation at the centrosome that acts through modulation of the transport of pericentriolar satellites, and consequently, of the organisation of cell structure
22264561 KIAA1377 and C5orf42 gene synergistically play a role as susceptibility genes for monomelic amyotrophy.

AA Sequence

MLAGRPGTRSAVGELGTESSDNLDRAPLGPRESGGHHRPGSYLDMKIHLEKNLEEERQILLQQQKICRNR      1 - 70
ARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPL     71 - 140
EEALKQIQESNLKSEVNLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLAT    141 - 210
SKNVFQLKLEETQKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEHEEIYLTLNKEHSTSIQRNT    211 - 280
ISLKPANMQSTNLSCFDEDKLAFSKTQHINNWLTNLDASNTQNVTAFSDILSKSNVLPSWEYFNSKEQNP    281 - 350
SPLNGTVERATNTANNSVPFVSSPPMFVLDKKCEKTSETSTMRTTDSTSGAFKRERPLVTESPTFKFSKS    351 - 420
QSTSDSLTQEVATFPDQEKYSELNQENGTTSIPTSCVPVATPLVLPSNIQSARPSAKNSIHIKEIDAVQC    421 - 490
SDKLDELKDGKEEEIKYFNCNKEELPLFSDSFQDAYIPHNPDSKDEKQKLAETSSLSNVTSNYDFVGQHK    491 - 560
KMKYNIHERNGVRFLKSILKKESKYEHGYLKALIINQSFKFGNQKAAAIRDSIELTKEKGAEIPKTIKKL    561 - 630
RWFDETSNIENNAENSHSLKNKTGTTQQHSQQFHIQSGAGSNIISVSTCAVNSADTKKSREDSISENVTT    631 - 700
LGGSGADHMPLNCFIPSGYNFAKHAWPASKKEESKIPVHDDSKTKQGKPQRGRAKIIRKPGSAKVQSGFI    701 - 770
CTNRKGAVIQPQSASKVNIFTQAQGKLIIPCPPPQSTSNIRSGKNIQVSQCQPVTPENPQNIITHNSFNS    771 - 840
KHVLPTEHSLNQWNQESSSPLSNACSDLVTVIPSLPSYCSSECQTFAKINHSNGTQAVARQDATLYCTQR    841 - 910
SPVCEESYPSVTLRTAEEESVPLWKRGPNVLHQNKRATGSTVMRRKRIAETKRRNILEQKRQNPGSVGQK    911 - 980
YSEQINNFGQSVLLSSSEPKQTTRGTSYIEEVSDSTSEFLMAENLVKASVPEDEILTVLNSKQIQKSNLP    981 - 1050
LNKTQQFNICTLSAEEQKILESLNDLSERLHYIQESICKNPSIKNTLQIIPLLEKREDRTSSCRDKR      1051 - 1117
//

Text Mined References (14)

PMID Year Title
24867236 2014 Cep126 is required for pericentriolar satellite localisation to the centrosome and for primary cilium formation.
22712476 2012 Identification of novel mitosis regulators through data mining with human centromere/kinetochore proteins as group queries.
22264561 2012 Exome sequencing identifies KIAA1377 and C5orf42 as susceptibility genes for monomelic amyotrophy.
19799413 2009 From midbody protein-protein interaction network construction to novel regulators in cytokinesis.
16554811 2006 Human chromosome 11 DNA sequence and analysis including novel gene identification.
16169070 2005 A human protein-protein interaction network: a resource for annotating the proteome.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15383276 2004 A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12812986 2003 DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12107411 2002 Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts.
10718198 2000 Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.
8889548 1996 Normalization and subtraction: two approaches to facilitate gene discovery.