| Tbio | Cdc42 effector protein 1 |
Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts.
CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008]
CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| glioblastoma | 5635 | 1.1e-07 |
| atypical teratoid / rhabdoid tumor | 4971 | 1.5e-02 |
| adult high grade glioma | 3701 | 1.6e-02 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | 1.300 | 1.6e-02 |
| atypical teratoid / rhabdoid tumor | 1.100 | 1.5e-02 |
| glioblastoma | 2.000 | 1.1e-07 |
MPGPQGGRGAATMSLGKLSPVGWVSSSQGKRRLTADMISHPLGDFRHTMHVGRGGDVFGDTSFLSNHGGS 1 - 70 SGSTHRSPRSFLAKKLQLVRRVGAPPRRMASPPAPSPAPPAISPIIKNAISLPQLNQAAYDSLVVGKLSF 71 - 140 DSSPTSSTDGHSSYGLDSGFCTISRLPRSEKPHDRDRDGSFPSEPGLRRSDSLLSFRLDLDLGPSLLSEL 141 - 210 LGVMSLPEAPAAETPAPAANPPAPTANPTGPAANPPATTANPPAPAANPSAPAATPTGPAANPPAPAASS 211 - 280 TPHGHCPNGVTAGLGPVAEVKSSPVGGGPRGPAGPALGRHWGAGWDGGHHYPEMDARQERVEVLPQARAS 281 - 350 WESLDEEWRAPQAGSRTPVPSTVQANTFEFADAEEDDEVKV 351 - 391 //
