| Tdark | Coiled-coil domain-containing protein 85C |
May play an important role in cortical development, especially in the maintenance of radial glia.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| psoriasis | 6694 | 3.3e-16 |
| Astrocytoma, Pilocytic | 3081 | 7.8e-05 |
| group 4 medulloblastoma | 1855 | 5.0e-04 |
| ovarian cancer | 8520 | 9.6e-04 |
| osteosarcoma | 7950 | 8.8e-03 |
| glioblastoma | 5792 | 1.1e-02 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 1.4e-02 |
| subependymal giant cell astrocytoma | 2287 | 2.4e-02 |
| pancreatic ductal adenocarcinoma liver metastasis | 1962 | 3.6e-02 |
| spina bifida | 1074 | 4.9e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Hydrocephalus | 152 | 4.191 | 2.1 |
| Disease | log2 FC | p |
|---|---|---|
| Astrocytoma, Pilocytic | -1.200 | 7.8e-05 |
| glioblastoma | -1.100 | 1.1e-02 |
| group 4 medulloblastoma | -1.400 | 5.0e-04 |
| intraductal papillary-mucinous neoplasm ... | 1.100 | 1.4e-02 |
| osteosarcoma | -1.177 | 8.8e-03 |
| ovarian cancer | -1.200 | 9.6e-04 |
| pancreatic ductal adenocarcinoma liver m... | -1.069 | 3.6e-02 |
| psoriasis | 1.400 | 3.3e-16 |
| spina bifida | -1.283 | 4.9e-02 |
| subependymal giant cell astrocytoma | -1.346 | 2.4e-02 |
| Accession | A6NKD9 |
| Symbols |
MAKPAATAAAASEELSQVPDEELLRWSKEELARRLRRAEGEKVGLMLEHGGLMRDVNRRLQQHLLEIRGL 1 - 70 KDVNQRLQDDNQELRELCCFLDDDRQKGRKLAREWQRFGRHAAGAVWHEVARSQQKLRELEARQEALLRE 71 - 140 NLELKELVLLLDEERAALAATGAASGGGGGGGGAGSRSSIDSQASLSGPLSGGAPGAGARDVGDGSSTSS 141 - 210 AGSGGSPDHHHHVPPPLLPPGPHKAPDGKAGATRRSLDDLSAPPHHRSIPNGLHDPSSTYIRQLESKVRL 211 - 280 LEGDKLLAQQAGSGEFRTLRKGFSPYHSESQLASLPPSYQDSLQNGPACPAPELPSPPSAGYSPAGQKPE 281 - 350 AVVHAMKVLEVHENLDRQLQDSCEEDLSEKEKAIVREMCNVVWRKLGDAASSKPSIRQHLSGNQFKGPL 351 - 419 //
