Property Summary

NCBI Gene PubMed Count 10
PubMed Score 3.35
PubTator Score 3.58

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (2)

Disease Target Count P-value
Breast cancer 3098 2.2e-58
psoriasis 6685 4.1e-17
Disease Target Count Z-score Confidence
Male infertility 170 3.176 1.6

Expression

  Differential Expression (2)

Disease log2 FC p
Breast cancer -2.000 2.2e-58
psoriasis -1.800 4.1e-17

Gene RIF (3)

PMID Text
20628086 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19913121 Observational study of gene-disease association. (HuGE Navigator)
12029070 Capping protein alpha3 may play a physiologically important role in sperm architecture as well as in fertility of the human male.

AA Sequence

MTLSVLSRKDKERVIRRLLLQAPPGEFVNAFDDLCLLIRDEKLMHHQGECAGHQHCQKYSVPLCIDGNPV      1 - 70
LLSHHNVMGDYRFFDHQSKLSFKYDLLQNQLKDIQSHGIIQNEAEYLRVVLLCALKLYVNDHYPKGNCNM     71 - 140
LRKTVKSKEYLIACIEDHNYETGECWNGLWKSKWIFQVNPFLTQVTGRIFVQAHFFRCVNLHIEISKDLK    141 - 210
ESLEIVNQAQLALSFARLVEEQENKFQAAVLEELQELSNEALRKILRRDLPVTRTLIDWHRILSDLNLVM    211 - 280
YPKLGYVIYSRSVLCNWII                                                       281 - 299
//

Text Mined References (11)

PMID Year Title
23903073 2013 Genome-wide association study of the five-factor model of personality in young Korean women.
21630459 2011 Proteomic characterization of the human sperm nucleus.
20628086 2010 Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
19922875 2009 The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.
19913121 2009 Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12029070 2002 Molecular cloning and characterization of the human orthologue of male germ cell-specific actin capping protein alpha3 (cpalpha3).
10524250 1999 Genomic analysis of male germ cell-specific actin capping protein alpha.
7957958 1994 Isolation and characterization of cDNA clones specifically expressed in testicular germ cells.