Protein Summary
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
- ENST00000341394
- ENSP00000340329
- ENSG00000135387
- ENST00000389645
- ENSP00000374296
- ENST00000530820
- ENSP00000434204
- ENST00000532820
- ENSP00000434150
- GPIAP1
- GPIP137
- M11S1
- RNG105
- M11S1
- GPIAP1
- RNG105
- GPIP137
- GRIP137
- p137GPI
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
microRNA | 0.99 | ||
disease perturbation | 0.95 | ||
interacting protein | 0.95 | ||
transcription factor perturbation | 0.94 | ||
kinase perturbation | 0.91 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 57.7 (req: < 5)
Gene RIFs: 29 (req: <= 3)
Antibodies: 287 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 57.7 (req: >= 5)
Gene RIFs: 29 (req: > 3)
Antibodies: 287 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0