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Tbio
CAND2
Cullin-associated NEDD8-dissociated protein 2

Protein Summary
Description
Probable assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295989
  • ENSP00000295989
  • ENSG00000144712
  • ENST00000456430
  • ENSP00000387641

Symbol
  • KIAA0667
  • TIP120B
  • Tp120b
  • TIP120B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.8
tissue sample
0.65
cell type or tissue
0.63
biological process
0.61
virus perturbation
0.5


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.65   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 61   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.65   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0