| Tbio | Neuron-specific vesicular protein calcyon |
Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis.
The protein encoded by this gene is a type II single transmembrane protein. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with D1 dopamine receptor and may interact with other DA receptor subtypes and/or GPCRs. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a type II single transmembrane protein. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with D1 dopamine receptor and may interact with other DA receptor subtypes and/or GPCRs. [provided by RefSeq, Jul 2008]
Comments
| Disease | Target Count |
|---|---|
| Cocaine Dependence | 51 |
| Schizophrenia | 1160 |
| Disease | Target Count | P-value |
|---|---|---|
| oligodendroglioma | 2850 | 2.5e-20 |
| Astrocytoma, Pilocytic | 3081 | 3.1e-15 |
| glioblastoma | 5792 | 1.5e-11 |
| atypical teratoid / rhabdoid tumor | 5112 | 3.1e-10 |
| primitive neuroectodermal tumor | 3035 | 1.0e-06 |
| group 3 medulloblastoma | 4104 | 1.7e-06 |
| pituitary cancer | 1972 | 7.7e-06 |
| adult high grade glioma | 3801 | 1.5e-05 |
| medulloblastoma, large-cell | 6241 | 7.6e-05 |
| astrocytic glioma | 2597 | 1.8e-03 |
| Pick disease | 1894 | 1.5e-02 |
| ependymoma | 4679 | 2.7e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Ectopic pregnancy | 16 | 3.096 | 1.5 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -1.400 | 1.5e-05 |
| astrocytic glioma | -2.600 | 1.8e-03 |
| Astrocytoma, Pilocytic | -3.900 | 3.1e-15 |
| atypical teratoid / rhabdoid tumor | -1.400 | 3.1e-10 |
| ependymoma | -2.400 | 2.7e-02 |
| glioblastoma | -3.500 | 1.5e-11 |
| group 3 medulloblastoma | -3.800 | 1.7e-06 |
| medulloblastoma, large-cell | -1.300 | 7.6e-05 |
| oligodendroglioma | -2.900 | 2.5e-20 |
| Pick disease | -2.100 | 1.5e-02 |
| pituitary cancer | 1.700 | 7.7e-06 |
| primitive neuroectodermal tumor | -1.200 | 1.0e-06 |
