| Tbio | Cactin |
Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. May play a role during early embryonic development. Probably involved in pre-mRNA splicing.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| glioblastoma | 5792 | 5.9e-06 |
| medulloblastoma, large-cell | 6241 | 1.8e-05 |
| adult high grade glioma | 3801 | 5.6e-05 |
| osteosarcoma | 7950 | 9.0e-04 |
| ependymoma | 4679 | 5.6e-03 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Dilated cardiomyopathy | 56 | 3.38 | 1.7 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -1.500 | 5.6e-05 |
| ependymoma | 1.400 | 5.6e-03 |
| glioblastoma | 1.100 | 5.9e-06 |
| medulloblastoma, large-cell | 1.100 | 1.8e-05 |
| osteosarcoma | 1.145 | 9.0e-04 |
| Species | Source | Disease |
|---|---|---|
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA | ||
| Inparanoid OMA |
MGRDTRSRSRSAGRRGRRRQSQSGSRSRSRSHGRRNRRRREDEGRRRRRRRSRERRSDSEEERWQRSGMR 1 - 70 SRSPPRPKWHSRDGSSQSDSGEEQSRGQWARRRRRARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSL 71 - 140 QERLRLREERKQQEELMKAFETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDNPFGDNNLLGTF 141 - 210 IWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTW 211 - 280 EEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLAVEMHEPYTFLNGLTVADMEDLLEDIQV 281 - 350 YMELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQG 351 - 420 IEGKIRAGGPNLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSP 421 - 490 SRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLDDYDAGRYS 491 - 560 PRLLTAHELPLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGK 561 - 630 AYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACA 631 - 700 DNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 701 - 758 //
