| Tbio | Calcium-binding protein 39-like |
Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity).
Comments
| Disease | Target Count | P-value |
|---|---|---|
| non-small cell lung cancer | 2890 | 3.4e-21 |
| lung adenocarcinoma | 2716 | 3.3e-13 |
| ovarian cancer | 8520 | 7.8e-12 |
| adrenocortical carcinoma | 1428 | 5.4e-11 |
| lung carcinoma | 2843 | 2.8e-08 |
| Breast cancer | 3578 | 4.1e-08 |
| medulloblastoma, large-cell | 6241 | 4.7e-07 |
| breast carcinoma | 1638 | 7.1e-06 |
| pituitary cancer | 1972 | 7.6e-05 |
| atypical teratoid / rhabdoid tumor | 5112 | 1.7e-04 |
| lung cancer | 4740 | 5.8e-04 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2989 | 7.5e-04 |
| adult high grade glioma | 3801 | 8.0e-04 |
| glioblastoma | 5792 | 1.5e-03 |
| medulloblastoma | 720 | 2.2e-03 |
| interstitial cystitis | 2312 | 2.7e-03 |
| psoriasis | 6694 | 3.1e-03 |
| intraductal papillary-mucinous adenoma (IPMA) | 2955 | 1.9e-02 |
| osteosarcoma | 7950 | 2.7e-02 |
| spina bifida | 1074 | 3.6e-02 |
| colon cancer | 1478 | 4.2e-02 |
| ependymoma | 4679 | 4.8e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Acute monocytic leukemia | 13 | 4.344 | 2.2 |
| Disease | log2 FC | p |
|---|---|---|
| adrenocortical carcinoma | -1.873 | 5.4e-11 |
| adult high grade glioma | -2.100 | 8.0e-04 |
| atypical teratoid / rhabdoid tumor | 1.200 | 1.7e-04 |
| Breast cancer | -1.200 | 4.1e-08 |
| breast carcinoma | -1.100 | 7.1e-06 |
| colon cancer | -1.300 | 4.2e-02 |
| ependymoma | 1.200 | 4.8e-02 |
| glioblastoma | -1.400 | 1.5e-03 |
| interstitial cystitis | -1.400 | 2.7e-03 |
| intraductal papillary-mucinous adenoma (... | -1.300 | 1.9e-02 |
| intraductal papillary-mucinous carcinoma... | -1.300 | 7.5e-04 |
| lung adenocarcinoma | -1.300 | 3.3e-13 |
| lung cancer | -1.600 | 5.8e-04 |
| lung carcinoma | -1.200 | 2.8e-08 |
| medulloblastoma | -1.400 | 2.2e-03 |
| medulloblastoma, large-cell | -3.000 | 4.7e-07 |
| non-small cell lung cancer | -1.532 | 3.4e-21 |
| osteosarcoma | 1.985 | 2.7e-02 |
| ovarian cancer | -2.600 | 7.8e-12 |
| pituitary cancer | 1.200 | 7.6e-05 |
| psoriasis | -1.100 | 3.1e-03 |
| spina bifida | -1.657 | 3.6e-02 |
MKKMPLFSKSHKNPAEIVKILKDNLAILEKQDKKTDKASEEVSKSLQAMKEILCGTNEKEPPTEAVAQLA 1 - 70 QELYSSGLLVTLIADLQLIDFEGKKDVTQIFNNILRRQIGTRSPTVEYISAHPHILFMLLKGYEAPQIAL 71 - 140 RCGIMLRECIRHEPLAKIILFSNQFRDFFKYVELSTFDIASDAFATFKDLLTRHKVLVADFLEQNYDTIF 141 - 210 EDYEKLLQSENYVTKRQSLKLLGELILDRHNFAIMTKYISKPENLKLMMNLLRDKSPNIQFEAFHVFKVF 211 - 280 VASPHKTQPIVEILLKNQPKLIEFLSSFQKERTDDEQFADEKNYLIKQIRDLKKTAP 281 - 337 //
