UPF0587 protein C1orf123

Property Summary

NCBI Gene PubMed Count	8
PubMed Score	1.25

PubTator Score	2.33

Knowledge Summary

Patent

No data available

TINX Plot

Disease (2)

Expression Atlas
JensenLab Text Mining

Disease	Target Count	P-value
ovarian cancer	8520	2.5e-08
non primary Sjogren syndrome sicca	891	2.9e-02

Disease	Target Count	Z-score	Confidence
Polycystic ovary syndrome	360	3.563	1.8

Expression

Specificity
Differential

Differential Expression (2)

Disease	log2 FC	p
non primary Sjogren syndrome sicca	1.100	2.9e-02
ovarian cancer	-1.200	2.5e-08

Uterus 17,618

Artery - Tibial 17,631

Colon - Sigmoid 18,089

Ovary 17,971

Artery - Coronary 17,949

Nerve - Tibial 18,007

Artery - Aorta 17,896

Vagina 17,834

Esophagus - Muscularis 18,017

Esophagus - Gastroesophageal Junction 18,000

Adipose - Subcutaneous 18,110

Adipose - Visceral (Omentum) 17,937

Thyroid 18,024

Breast - Mammary Tissue 18,103

Spleen 17,614

Cells - Transformed fibroblasts 17,577

Stomach 17,879

Prostate 18,213

Testis 18,518

Brain - Cerebellar Hemisphere 18,015

Pituitary 18,147

Brain - Cerebellum 17,983

Brain - Spinal cord (cervical c-1) 17,973

Adrenal Gland 18,071

Brain - Frontal Cortex (BA9) 18,069

Muscle - Skeletal 17,778

Brain - Nucleus accumbens (basal ganglia... 18,024

Lung 18,057

Brain - Caudate (basal ganglia) 18,001

Brain - Cortex 18,039

Small Intestine - Terminal Ileum 17,954

Cells - EBV-transformed lymphocytes 18,186

Brain - Hypothalamus 18,169

Brain - Anterior cingulate cortex (BA24) 17,989

Brain - Substantia nigra 17,981

Brain - Amygdala 18,006

Skin - Sun Exposed (Lower leg) 17,968

Brain - Hippocampus 18,011

Skin - Not Sun Exposed (Suprapubic) 18,081

Brain - Putamen (basal ganglia) 17,863

Heart - Atrial Appendage 17,896

Esophagus - Mucosa 18,076

Minor Salivary Gland 18,005

Colon - Transverse 17,825

Kidney - Cortex 17,329

Heart - Left Ventricle 18,006

Liver 18,071

Whole Blood 17,439

Pancreas 18,123

Fetal Testis 7,955

Adult Testis 10,836

Adult Ovary 10,192

Fetal Ovary 9,118

CD8 Cells 9,840

Adult Urinary Bladder 7,592

Adult Pancreas 9,168

Adult Prostate 8,952

B Cells 9,086

Fetal Heart 9,228

NK Cells 8,475

CD4 Cells 7,773

Platelets 6,131

Adult Retina 10,115

Fetal Gut 8,640

Adult Rectum 8,022

Adult Gallbladder 7,612

Adult Colon 7,915

Fetal Liver 8,402

Adult Adrenal 8,475

Adult Spinal Cord 7,594

Fetal Brain 7,866

Adult Kidney 6,723

Adult Lung 6,663

Adult Esophagus 4,936

Adult Liver 9,113

Adult Heart 6,506

Adult Frontal Cortex 9,048

Monocytes 7,422

Adrenal gland

Blood platelet

Brain

Colon

Frontal lobe

Gall bladder

Gut

Heart

Kidney

Liver

Lung

B-lymphocyte

Monocyte

Natural killer cell

Esophagus

Ovary

Pancreas

Placenta 6,083

Prostate gland

Rectum

Retina

Spinal cord

Testis

Urinary bladder

BTO:0004410

BTO:0005453

adipose tissue 15,837

adrenal gland 15,963

appendix 16,247

bone marrow 14,571

breast 16,063

cerebral cortex 16,630

cervix, uterine 15,871

colon 15,959

duodenum 15,975

endometrium 16,349

epididymis 15,863

esophagus 15,898

fallopian tube 16,245

gallbladder 16,333

heart muscle 14,972

kidney 15,917

liver 14,587

lung 16,312

lymph node 15,833

ovary 15,408

pancreas 14,070

parathyroid gland 14,769

placenta 15,937

prostate 16,460

rectum 15,705

salivary gland 14,981

seminal vesicle 15,918

skeletal muscle 14,011

skin 16,206

small intestine 16,154

smooth muscle 15,857

spleen 15,972

stomach 16,099

testis 17,936

thyroid gland 15,959

tonsil 15,400

urinary bladder 15,814

Liver and Pancreas 16,750

Digestive Tract 17,369

Urinary Tract 16,678

Endocrine System 18,159

Blood and immune system 16,909

Respiratory system 16,393

Female tissues 17,400

Male tissues 17,142

Skin and soft tissues 17,230

Nervous System 16,725

Cardiovascular System 15,192

Brain 7,346

Erythroleukemia cell 4,300

Liver 5,008

Interstitial cell of Cajal 192

See source...

Electric organ 28

See source...

Synonym

Accession	Q9NWV4
Symbols

Gene

C1orf123

Ortholog (17)

Species	Source	Disease
Pig 10,168	OMA EggNOG
Opossum 12,230	Inparanoid OMA EggNOG
Platypus 5,703	OMA EggNOG
Chicken 7,827	Inparanoid OMA
Anole lizard 10,588	OMA EggNOG
Xenopus 10,468	Inparanoid OMA EggNOG
Zebrafish 9,726	Inparanoid OMA EggNOG
C. elegans 3,179	Inparanoid OMA
Fruitfly 3,050	Inparanoid EggNOG
S.cerevisiae 1,799	Inparanoid OMA EggNOG
Chimp 14,140	OMA EggNOG
Macaque 12,761	Inparanoid OMA EggNOG
Mouse 16,570	Inparanoid OMA EggNOG
Rat 15,117	Inparanoid OMA EggNOG
Dog 15,073	OMA EggNOG
Horse 14,252	OMA EggNOG
Cow 15,320	Inparanoid OMA EggNOG

UniProt Keyword (4)

Complete proteome 20,231

Reference proteome 20,231

Phosphoprotein 8,216

Direct protein sequencing 2,872

GO Component (1)

extracellular exosome 2,767

Compartment GO Term (3)

Cholinergic synapse 15

Cytosol 6,686

cellular_component 18,320

HCA RNA Cell Line (56)

A-431 16,131

A549 15,174

AF22 16,160

AN3-CA 15,648

ASC TERT1 14,842

BEWO 16,726

BJ 15,448

BJ hTERT+ 15,353

BJ hTERT+ SV40 Large T+ 15,609

BJ hTERT+ SV40 Large T+ RasG12V 15,493

See all...

Protein-protein Interaction (4)

ERI3 BICD2 PBX3 RPS4Y1

AA Sequence

MGKIALQLKATLENITNLRPVGEDFRWYLKMKCGNCGEISDKWQYIRLMDSVALKGGRGSASMVQKCKLC      1 - 70
ARENSIEILSSTIKPYNAEDNENFKTIVEFECRGLEPVDFQPQAGFAAEGVESGTAFSDINLQEKDWTDY     71 - 140
DEKAQESVGIYEVTHQFVKC                                                      141 - 160
//

Text Mined References (11)

Summary
Details

	PMID	Year	Title